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ONCONASE(R) has Potential as Chemopreventive Agent in Mesothelioma ...

... In a series of poster presentations, Dr.

Carbone highlighted the growing worldwide problem of asbestos exposure and its link to malignant Dr.

Carbone presented data that show the early detection in patients at high risk for developing malignant Furthermore, he pointed out that ONCONASE's favorable toxicity profile and its well-documented mechanism of action, which directly affects the pathway that has been shown to cause asbestos carcinogenesis, position ONCONASE for potential early administration to populations "at-risk" for If clinically validated, such a new approach might enable physicians to use ONCONASE as a chemopreventive agent to potentially prevent the onset of "The potential of ONCONASE as an early first-line preventative treatment for Carbone.

"With approximately more than 25 million asbestos exposure cases reported worldwide, we believe that ONCONASE might play a greater role in the treatment protocols for a much larger population than was originally envisioned for this dismal disease." Dr.

Car...

'No justice' over payout

...Up to £10,000 of that was classed as bereavement compensation, the maximum pay out for victims in England, but just over the border in Scotland compensation can reach three times the amount.

"I just think everyone should be treated equally," said 56-year-old Mrs Coles.

"But to be honest, the money means nothing to me - no amount can make up for losing Jim." A pipe fitter and father of two, Jim served 44 years at the Metro-Cammell yard in Washwood Heath where he used to scrape asbestos off pipes by hand.

Story continues ADVERTISEMENT But after more than four decades he was made redundant in 2004 and within two days was diagnosed with the inoperable disease.

He died aged 60.

"He was in agony for 13 months," added Mrs Coles, "he suffered terribly.

I'm still devastated - to me they've robbed him of his life and robbed me of mine." Lawyers acting for Mrs Coles won the settlement from Metro-Cammell's insurers last November, two years after Jim was diagnosed.

The sum was agreed by conference call hours before the case was due to be heard at Birmingham County Court.

Ian McFall, head of asbestos policy at Thompsons Solicitors, said: "The law must be changed to ensure families in England and Wales are entitled to the same level of compensation for bereavement as the equivalent family in Scotland." Top Printable version Copyright and Trade Mark Notice © owned by or licensed to Midland Newspapers Limited 2007 icSolihull™ is a tra...

Alfacell says Onconase shows preclinical promise

...A natural protein isolated from the leopard frog, Onconase has been shown in the laboratory and clinic to target cancer cells while sparing normal cells.

RELATED NEWS Alfacell drug designated orphan product31 Jan 2007 Alfacell forms lymphoma collaboration12 Jul 2006 Alfacell says Onconase shows anti-tumor activity17 Nov 2006 COMPANIES MENTIONED Alfacell Corporation YOUR OPINION...

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