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Lilly Oncology focused on pharmacogenomic at AACR meeting

...GEMZAR, which celebrated its 10th anniversary as a marketed product for patients in the United States last year, forms the basis of two trials being presented at AACR.

GEMZAR is approved in the treatment of pancreatic, NSCLC, breast and ovarian cancers in the United States.

In addition, outside of the US, several countries have the additional indication in metastatic bladder, cervical and biliary tract cancers.

Enzastaurin is an investigational oral, serine threonine kinase inhibitor which selectively targets the PKC-(beta) and PI3/AKT signaling pathways and is the subject of seven studies being presented at AACR.

Enzastaurin is currently being investigated in a global Phase III PRELUDE trial for the treatment of diffuse large B-cell lymphoma, the most common type of non-Hodgkin's lymphoma.

Enzastaurin is also being evaluated in Phase II studies across several tumor types including: breast, colon, non-small cell lung, pancreas, ovarian and prostate cancers.

In partnership with the AACR, Lilly Oncology will also recognize innovative and collaborative research with the sponsorship and presentation of the first-ever Team Science Award and the annual G.H.A.

Clowes Memorial Award.

The most common adverse events (grades 3/4) with ALIMTA in combination with cisplatin for the treatment of patients with MPM were neutropenia (24 per cent); leukopenia (16 per cent); anemia (6 per cent); thrombocytopenia (5 per cent); inf...

ASBESTOS LAW 'UNFAIR'

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Lawyers want asbestos compensation in England brought up to match ...

...They carry the emotional burden for the rest of their lives." Last night, Des McNulty, a leading campaigner for victims of He added: "There is a strong consensus in Scotland for proper levels of compensation for asbestos victims and I would hope that similar consideration is given to those suffering from this dreadful disease south of the border." It is a form of cancer that attacks the lining of the lungs after exposure to asbestos.

About1900 people die from it in the UK every year.

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