Mesothelioma

...GEMZAR, which celebrated its 10th anniversary as a marketed product for patients in the United States last year, forms the basis of two trials being presented at AACR.

GEMZAR is approved in the treatment of pancreatic, NSCLC, breast and ovarian cancers in the United States.

In addition, outside of the US, several countries have the additional indication in metastatic bladder, cervical and biliary tract cancers.

Enzastaurin is an investigational oral, serine threonine kinase inhibitor which selectively targets the PKC-(beta) and PI3/AKT signaling pathways and is the subject of seven studies being presented at AACR.

Enzastaurin is currently being investigated in a global Phase III PRELUDE trial for the treatment of diffuse large B-cell lymphoma, the most common type of non-Hodgkin's lymphoma.

Enzastaurin is also being evaluated in Phase II studies across several tumor types including: breast, colon, non-small cell lung, pancreas, ovarian and prostate cancers.

In partnership with the AACR, Lilly Oncology will also recognize innovative and collaborative research with the sponsorship and presentation of the first-ever Team Science Award and the annual G.H.A.

Clowes Memorial Award.

The most common adverse events (grades 3/4) with ALIMTA in combination with cisplatin for the treatment of patients with MPM were neutropenia (24%); leukopenia (16%); anemia (6%); thrombocytopenia (5%); infection without ...

... New questions in hostage saga : Shropshire Star Site Search: Home Bookmark This Site Sunday, 15th April 2007, 5:00 GMT New questions in hostage saga New questions emerged today over the Ministry of Defence’s handling of the decision to allow the Iran hostages to sell their stories to the media.

Reports claimed MoD guidelines required interview requests from newspapers be approved by the department’s press office.

Separate reports emerged suggesting the MoD did not respond to an offer of help from the press watchdog over the handling of the captives.

Newspaper reports said a departmental document, entitled Defence Council Instructions General, requires that “authorisation should be obtained from the chief press officers in the D News organisation”.

The Tories said the revelation undermined Defence Secretary Des Browne’s account of how the decision was made.

Mr Browne had stressed that the actual decision had been taken by the Navy, and he was only asked to “note” the reasons behind it last Friday.

Shadow defence secretary Dr Liam Fox said: “The disclosure of these regulations, contradicting the Defence Secretary’s version of events, raises yet more questions.” An MoD spokeswoman said: “The Secretary...

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